Now my pcp wants to put me on anxiety med and I'm not OK with that. You can also drink a water-based beverage to wash it all down, notes Dr. Perez-Gallardo. I have depression but no antidepressant has ever worked for me. DOCTORS APPOINTMENT TOMORROW FOR A DIURETIC FOR THE FLUID RETENTION. Has worked extremely well and also supports my waning, menopausal sex drive. My OBGYN says I can continue to take it as long as I'm finding it beneficial. Multivitamins can be trickier: They often contain both water- and fat-soluble vitamins. This medicine should come with a patient information leaflet. I feel great on this drug and have had no side effects. Customer: will it make me sleepy Monika Hearne, M.D. Drug information provided by: IBM Micromedex. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Report any unusual vaginal bleeding right away. Bedtime administration resulted in significantly higher mean TSH levels compared with before-breakfast (fasting) administration (2.19 mIU per L vs. 1.06 mIU per L; P < .001), but significantly lower mean TSH levels compared with breakfast (nonfasting) administration (2.19 mIU per L vs. 2.93 mIU per L; P = .026). I was hoping after 8 years, I might not need Prempro any longer so weaned myself off. Do not take this medicine in larger amounts or for longer than recommended. Customer: do I have to eat before I take it Monika Hearne, M.D. After taking it for about 8 months it stopped working. Estrogen is necessary for many processes in the body. I very reluctantly asked my doctor for hormone replacement. In clinical studies of paroxetine for depression, over 20% of people experienced sleepiness, and insomnia occured in over 10%. :) At least I now know why and that I'm not alone. And while youre at it, also take 400 micrograms of folic acid daily three months before you plan to get pregnant. The first study on this drug was totally flawed Standard dosage: 0.625 conjugated estrogen/2.5 mg MPA (daily with Prempro; with Premphase, you take the progestin only 2 weeks out of the month). Super frustrating because it started out so promising. You may opt-out of email communications at any time by clicking on I was having hot flashes (but rather "warm" flashes for me) all day and night. I cant stress enough yes it helped my mood and my hot flashes but in the end Ive been going thru a nightmare . Also, not as hungry as normal. Empty the contents of a 2.5 milligrams (mg) packet of powder into a container containing 5 mL of water. That was perfect. I quit taking it and the yeast infections never came back but left me. Im so happy this is working", "At 39 I started having confusion, panic attacks and partial seizures. F: 53 15 years.625 1X D . Elevated evening estrogens interfere with growth hormone release. Hope it keeps working. Have been taking Prempro for approx. Have sex - this is the fun bit. Take Prempro exactly as prescribed by your doctor. For oral dosage form (powder for suspension): To prevent upper gastrointestinal tract bleeding in seriously ill patients: AdultsThe first day: 40 milligrams (mg) for the first dose, then after 6 to 8 hours, a second 40 mg dose. Advertising revenue supports our not-for-profit mission. Im so happy prempro is working. The best time to take calcium depends on the kind you take, explains Dr. Perez-Gallardo. Hello ChildrenUse and dose must be determined by your doctor. The dose is usually 5 to 20 mg once a day before a meal. And sex.forget it! My psychiatrist suggested this and I was able to function again in all aspects of life. I just recently had a spot on my mammogram that scared me which turned out to be a cyst. The hormone replacement therapy's effects should be the same regardless of when it is taken. Has anyone tried Flax for menopausal symptoms? My mood actually seems to have improved but who knows this year has been crazy for all. On July 3 I had a mini stroke and was taken off of prempro immediately. D and calcium. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. dementia. Now my heat flashes, night sweats and weight gain has stopped! Read More Read Less. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. I do experience increased appetite, occasional constipation; gained 10 lbs. My husband retired a couple months ago so I lost insurance. My husband expressed concern at how my mood had collapsed, and I had to keep retreating to bed to nurse my headache. This content is owned by the AAFP. I believe they could make a synthetic with the same properties of horse urine but apparently they don't care or don't want to spend the money. We do not endorse non-Cleveland Clinic products or services. But using progesterone this way is counter to the design of the body because progesterone is naturally higher in the morning. This means progesterone is being used as a sleeping agent. optic disk edema . There is conflicting evidence. I was told that I was too old for hot flashes. Follow all directions on your prescription label. I'm sleeping at night. I took me about a month for me to not feel groggy and light headed. I began taking Prempro about 20 years ago and decided to quit and just suffer from the heat about a year and a half ago. I havent had a period for the last ten years. The drop in hormone levels at the end of the day actually signals the body that it needs to make another batch of hormones. I get frustrated when people say "It causes cancer and it isn't worth it just to cure hot flashes" First of all, there is just a small increase in the chance of breast cancer and you shouldn't take it if breast cancer runs in your family. This means progesterone is being used as a sleeping agent. deficiency of anti-clotting agents. Took about three weeks for me to notice any benefits: hot flashes were nearly gone, brain fog was lifting, mood was improving. Has not increased my desire for sex either. The effectiveness of levothyroxine for reducing TSH levels is most dependent on the timing of meals in relation to drug administration. GYN said I was in menopause (at 51) so started on Prempo (1.5 mg) two weeks ago. Have not had a period in 5 years and after starting on this, had discharge and slight spotting, always needing a pantie liner. This mixture must be swallowed immediately with a glass of cool water. My hot flashes have dwindled to just a slight warmth and I can tell my attitudes a lot different I can see the light again my menopause started in 2014 my last menstrual cycle was June 2017 it has been miserable until yesterday thank you, Started it in my 40s stopped at age 84 one year later got osteoporosis had terrible hot flashes and night sweats now back on doctor warned about blood clots, I started taking Prempro when I was 50. unusual vaginal bleeding that has not been checked by a doctor; a history of heart attack, stroke, or blood clot; an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. As 4 the severe side effects go through most drugs u take and u will see the same ones. - this has improved some, but not happy with the mood swings and spotting. Your doctor may adjust your dose as needed. Tonight will be my 4th dose and I honestly cannot wait to see how I feel after a week. include protected health information. Compare all 145 medications used in the treatment of Postmenopausal Symptoms. This medication saved my life and gave me a life worth living. The dose is usually 2.5 to 10 mg once a day before a meal. Good to hear from you again, Lisa. Call your doctor for medical advice about side effects. We only have one pharmacy in town. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Post-Menopausal Osteoporosis Prevention (23 reviews), Vaginal Inflammation due to Loss of Hormone Stimulation (5 reviews), Wasting of Tissues of the Vulva (1 reviews), Doctor started me on Prempro 0.625mg/2.5mg ("I start all my patients with this."). Version: 12.03, hydrochlorothiazide, alendronate, estradiol, Fosamax, Prolia, calcium carbonate, Premarin, Estrace, Tymlos, Yuvafem. Cleveland Clinic is a non-profit academic medical center. I wasn't sleeping, was difficult to work, and just plain miserable. Portions of this document last updated: Feb. 01, 2023. Mood swings are still there as well so Im hoping after 1 week I see a big change.. wish me luck", "I started Prempro in 2009, still taking it 9 years later at age 62. Prempro may increase your risk of developing a condition that may lead to uterine cancer. (Strength of Recommendation: C, disease-oriented outcome.) Ask your doctor if you have any questions. So, if paroxetine makes you sleepy, you can try taking it in the evening. Also want to mention that since menopause, I have zero Interest in sexual relations with my husband. Adults60 milligrams (mg) once a day before a meal. The second was much more positive and so no increase in cancer but couldn't determine whether it helped prevent heart attacks. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. and no matter what I do it wont budge. If you eat a nutritious, balanced diet, you do not need these supplements. Low and behold I was in full on menopause. If you are taking this medicine to treat an ulcer that is associated with an H. pylori infection, take it together with antibiotics (eg, amoxicillin, clarithromycin) at the same time of day. Take another single PrEP pill 24 hours after your last dose. The same side effects are a concern with PEP, but because the treatment only lasts one month, there is less concern about long-term issues. I was bleeding almost every day. Read More Read Less. Some forms of menopause hormone therapy may cause monthly bleeding. I've noticed I am less tolerable (that could be my age) of things I normally would be. Adults40 milligrams (mg) once a day for 4 to 8 weeks. I only toss my comforter once a night as opposed to many times. While they are important throughout pregnancy, the best time to start taking prenatal vitamins is before you're pregnant when you're planning to conceive, says Dr. Perez-Gallardo. I told him on more than one occasion that I thought it was hormone related and he didn't think so. I noticed a difference in 2 days! After a few weeks I started experiencing hot flashes and insomnia. It's now $162. Maddie6. My day sweats are no longer embarrassing, e.g. I started this medication about a week ago, and have not had any issues with it yet, but I have not had any relief with my hot flashes yet and was just curious what others thought. So will eating food cooked with oil. I'm waking up in the middle of the night. I have tried every natural and I was suffering. The best I have felt in years! If you cant eat this way at least one meal a day, you may benefit from taking vitamins. The first study on this drug was totally flawed A collection of FPINs Clinical Inquiries published in AFP is available at https://www.aafp.org/afp/fpin. Took it at noon. Follow your doctor's orders or the directions on the label. My thing was the night sweats, vaginal dryness, painful intercourse and no interest in sex at all which my husband was not thrilled about. ", "I was feeling stuck in perpetual PMS. Until 2002, many clinicians were also recommending it long term to prevent chronic health problems, including heart disease, stroke, and osteoporosis. Wow! What 11 year old wants sex? Do not open the capsule. I have never heard of that. I am on my second dose and l am looking forward to having back my quality of life! Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, How to Live Life Better With Your Migraine. I've read that flax an help quell our symptoms. My Dr gave me a prescription for Prempro. Take the medicine at the same time each day. Other than this I have had no other bad side effects; have been on this medicine now for approximately 6 months. This survey is being conducted by the WebMD marketing sciences department. . My symptoms I was having were hair loss, hot flashes and I was mean and hateful. Should I avoid certain foods while taking Prempro? This medicine should come with a Medication Guide. Your body makes testosterone, progesterone, estrogens, DHEA, cortisol, thyroid hormones, etc., on a 24 hour basis. Discuss the use of grapefruit products with your doctor. After one month, my hot flashes were the worst they had ever been and I had a continuous headache. They go by your income. Tell your doctor right away if you become pregnant during treatment. Viewer Questions from Good Morning America . A 2015 randomized, double-blind, placebo-controlled, crossover study compared the effects of morning (30 minutes before breakfast) vs. evening (60 minutes before dinner) administration of . My thing was the night sweats, vaginal dryness, painful intercourse and no interest in sex at all which my husband was not thrilled about. My doctor put me on a low dose which helped a little, then increased to 0.625mg. We comply with the HONcode standard for trustworthy health information. I started out at a full dose and quickly realized it was way too much. Downside it is expensive. I have new insurance, but my co-pay used to be $20.00. A: Prempro is a medicine that contains two kinds of hormones: estrogens and a progestin. Anyone try it or have a im a active, healthy 58 yr old woman. Children younger than 1 month of ageUse and dose must be determined by your doctor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Good Luck to all. Severe headaches,nausea, chest pains and severe mood swings. I had severe depression, and anxiety, I couldn't focus, and I couldn't function. My husband and kids say I'm more moody, and not myself. Learn more about Premarin . Calcium supplements come in two forms: calcium carbonate and calcium citrate. I took this medication for three days. Decrease your dosage of Prempro. . At about the 5 year mark, my doctor strongly encouraged that I wean off Prempro, informing me that my chances of breast cancer and/or stroke increases after 5 years. I am hoping for relief, as of right now nothing. Hormone therapy has long been the standard treatment for relieving menopausal symptoms: hot flashes, night sweats, and vaginal dryness. HRT works for me and I'll probably have to take it until I die. Copyright 1996-2023 Cerner Multum, Inc. vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding. No problems at all. Store at room temperature away from moisture, heat, and light. The benefits of Prempro do not out weight losing a life from heart failure. And sex.forget it! But before returning me to HRT she had me try venlafaxine. Take Hormones Once a Day in the Morningby Joseph J Collins, RN, ND. LOVING IT. Stopping Prempro. Any advice from anyone I would appreciate it. Sync your supplements with your schedule for maximum benefits. I've saved and am going to read it later. conjugated estrogens and medroxyprogesterone, Prempro pregnancy and breastfeeding warnings. The American Thyroid Association recommends that levothyroxine be consistently taken 60 minutes before breakfast or at bedtime, at least three hours after dinner.5. I found this very helpful", "I am a 56 year old women in post-menopause. Therefore, your condition should be evaluated every three to six months. These side-effects became unbearable so I had my doctor switch me to a bioidentical HRT. I plan to stop medication. She was reluctant but I had already tried black cohosh, green tea and 3 different OTC drugs that were supposed to relieve the hot flashes. Hi, I am a 62 year old woman, and after almost 12 years on Prempro, I decided it was time to stop taking it. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. ALSO FLUID RETENTION IS NOT WORTH THE 10 POUNDS IN TWO WEEKS. I had early onset menopause. Members of the network select questions based on their relevance to family medicine. The daily high and low values both signals the need for more hormone production, and help decrease the risk of developing hormone resistance a situation where the cells of the body become resistant to hormone messages because the hormones do not drop as they should. I would wake up at night and couldn't go back to sleep - no matter how hard I tried. scary. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
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